Streamline discovery of new therapeutic agents targeting GPCRs

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A video guide to unlocking a new dimension in Gq signaling with IP-One technology

GPCRs constitute the largest family of cell surface receptors and account for over one-third of drug screening efforts. IP-One technology capitalizes on native Gq signaling cascades to screen the pharmacological potency of compounds through the accumulation of inositol-1-phosphate, a metabolite of the Gq pathway. Watch this complimentary video to learn about:
  • Gq-coupled GPCR signaling cascades through activation of phospholipase C
  • Overcoming the drawbacks of Calcium Flux technology for more pharmacologically-relevant results
  • An efficient method for characterizing compounds acting on Gq-coupled receptors