Determination of association and dissociation rates constants using the Tag-lite platform

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Challenge the limits of binding kinetics studies

This Note describes how binding kinetics studies can be enriched with a Kon, Koff approach by providing critical data on how the association and dissociation rates of a receptor-ligand couple can be assessed thanks to streamlined, no wash Tag-lite assays. Learn how to process and analyze the data, and discover how receptor binding kinetics offers significant insights into your compound’s mode of action.

Features:

  • Materials and methods for the experiment
  • Data processing and result analysis
  • Examples from our R&D