Challenge the limits of binding kinetics studies
This Note describes how binding kinetics studies can be enriched with a Kon, Koff approach by providing critical data on how the association and dissociation rates of a receptor-ligand couple can be assessed thanks to streamlined, no wash Tag-lite assays. Learn how to process and analyze the data, and discover how receptor binding kinetics offers significant insights into your compound’s mode of action.
- Materials and methods for the experiment
- Data processing and result analysis
- Examples from our R&D
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