Multidimensional approach assays for extensive cell-based investigation

4 GPCR challenges, 1 solution

Binding kinetics, Gq/i/s/o signaling, and resulting phosphorylation… GPCR studies involve meeting all these challenges. This poster demonstrates how to take advantage of HTRF® and Tag-lite® technologies to address each challenge and thoroughly analyze and characterize compounds of interest in such GPCR oriented studies.

Features

• Introduction to the principle of HTRF® and Tag-lite® technologies
• Multidimensional approach illustrated with a Delta Opioid Receptor (DOR) and Protease-Activated Receptor 1 (PAR1)